Read the 2025 Impact Report

Prevention is about helping people stay healthy, connected, and supported.

What is Prevention?

Prevention is a deliberate commitment to health, wellness, and improved outcomes across the lifespan. SAFE Project intentionally integrates prevention best practices at every level, recognizing that full-spectrum prevention saves lives. Moving beyond a “Just Say No” approach, we embrace comprehensive strategies that incorporate primary, secondary, and tertiary prevention—both within our organization and in partnership with external stakeholders—creating meaningful impact together!

Substance use prevention is a proactive, ongoing process that aims to prevent the initiation and progressions substance use while mitigating associated harms. It is a multidisciplinary approach that reinforces protective factors and addresses risk while promoting overall health and well-being. Prevention plays a crucial role in fostering resilience and improving public health.



Preventing or delaying initial use through proactive measures.


Education, early support, and health promotion.

Early detection of, or reduction of, substance use.


Screening, early intervention, reducing further use, and preventing high-risk use.

Reducing harm associated with use and improving quality of life.


Harm reduction, treatment, and access for co-occurring healthcare.

Every week SAFE Project will release a Prevention Point that will center on the power of prevention. Topics will include how the field of prevention has shifted from focusing solely on fear/awareness/consequences to a more scientific/medical model of health promotion.

Each Prevention Point segment will share pointed messages to help readers better understand prevention concepts and guid them to additional information and resources that promote population health and life-changing impact.

From Awareness to Action:

Prevention is needed now more than ever as our world faces simultaneous epidemics around substance use, overdose, and mental health. Empowering prevention allies to join the charge is a crucial lifesaving step that begins with an understanding of what prevention is and what strategies are most effective.

Feature Spotlight

Filler Photo

Opioid Overdose Response Training

Prevention in the News

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