Read the 2025 Impact Report

Prevention is about helping people stay healthy, connected, and supported.

What is Prevention?

Prevention is taking steps to stop problems before they start—or to keep them from getting worse. It focuses on encouraging healthy choices, reducing risks, and ensuring people have the support they need so that individuals, families, and communities can thrive. SAFE Project intentionally integrates prevention best practices at every level, recognizing that full-spectrum prevention saves lives. Moving beyond a “Just Say No” approach, we embrace comprehensive strategies that incorporate primary, secondary, and tertiary prevention—both within our organization and in partnership with external stakeholders—creating meaningful impact together!

Substance use prevention is a proactive, ongoing process that aims to prevent the initiation and progressions substance use while mitigating associated harms. It is a multidisciplinary approach that reinforces protective factors and addresses risk while promoting overall health and well-being. Prevention is deliberate action in support of improved health and wellness.



Preventing or delaying initial use through proactive measures.


Education, early support, and health promotion.

Early detection of, or reduction of, substance use.


Screening, early intervention, reducing further use, and preventing high-risk use.

Reducing harm associated with use and improving quality of life.


Harm reduction, treatment, and access for co-occurring healthcare.

Welcome to Prevention Point, SAFE Project’s new series focusing on the power of prevention. Every other week, we’ll share easy-to-understand information, education, and helpful resources that will help you support prevention efforts. We understand that prevention approaches look different for everyone and that one size does not fit all. These approaches are yours to choose. Our goal is to provide clear, practical, and helpful choices to help you understand and support the needs of you, your families, and your communities.

From Awareness to Action:

Prevention is needed now more than ever as our world faces simultaneous epidemics around substance use, overdose, and mental health. Empowering prevention allies to join the charge is a crucial lifesaving step that begins with an understanding of what prevention is and what strategies are most effective.

Prevention Spotlights

Nina P.

Each year, we highlight authors and illustrators who promote prevention and resilience among our youth and young adults. Each author offers a unique perspective on the field of prevention and on the best approaches. In prevention work, facts and statistics are important – but they are rarely enough on their own to inspire change. Storytelling has the unique ability to move beyond information by creating common ground for human connection. Storytelling helps break the silence, foster connection, and develop coping and resiliency skills that buffer against risk.

At SAFE Project, we believe that prevention is more than a single campaign or initiative. We know that effective prevention is a proactive, ongoing process that requires year-round action by all of us. Our Prevention Perspectives webinars enhance impact by encouraging new perspectives, examining ways we can work together to reduce stigma, and maximizing innovative thinking and cross-sector collaboration.

Opioid Overdose Response Training